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Istalol Eye Drops

Generic name: timolol ophthalmicTIM-oh-lol-off-THAL-mik ]
Brand name: Istalol
Drug class: Ophthalmic glaucoma agents

Medically reviewed by Philip Thornton, DipPharm. Last updated on Apr 24, 2023.

What is Istalol?

Istalol is a beta-blocker that also reduces pressure inside the eye.

Istalol ophthalmic solution is used to treat open-angle glaucoma and other causes of high pressure inside the eye.

Istalol may also be used for purposes not listed in this medication guide.

Warnings

You should not use Istalol if you have asthma or severe COPD, or a serious heart condition (such as "sick sinus syndrome," 2nd or 3rd degree "AV block," severe heart failure, or very slow heartbeats).

Side effects may occur if timolol is absorbed into your bloodstream. Call your doctor right away if you have: chest pain, trouble breathing, slow heartbeats, muscle weakness, numbness or coldness in your hands or feet, unusual mood or behavior changes, or severe dizziness.

Do not allow the Istalol dropper to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Istalol can cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.

Before taking this medicine

You should not use Istalol if you are allergic to timolol, or if you have:

To make sure Istalol is safe for you, tell your doctor if you have ever had:

It is not known whether Istalol will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Timolol can pass into breast milk and may harm a nursing baby. You should not breastfeed while using this medicine.

Istalol is not approved for use by anyone younger than 2 years old.

How should I use Istalol?

Use Istalol exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Do not use this medicine while wearing contact lenses. Istalol may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using this medicine before putting in your contact lenses.

Wash your hands before using the eye drops.

To apply the Istalol eye drops:

Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.

Do not use the Istalol eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.

It may take a few weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment.

If you need surgery, including eye surgery, tell the surgeon ahead of time that you are using Istalol. You may need to stop using the medicine for a short time.

You should not stop using Istalol suddenly. Follow your doctor's instructions about tapering your dose.

Store Istalol eye drops at room temperature away from moisture, heat, and light. Do not freeze. Keep the bottle tightly closed when not in use. Keep each single-use ampule inside its foil pouch until you are ready to use your dose.

A single-use ampule is for one use only. Throw it away after one use, even if there is still medicine left inside.

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include dizziness, headache, slow heartbeats, and trouble breathing.

What should I avoid while using Istalol?

Istalol can cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you.

You may need to use other glaucoma medications in addition to Istalol. Do not use other eye medications unless your doctor tells you to.

Istalol side effects

Get emergency medical help if you have signs of an allergic reaction to Istalol: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when timolol is used in the eyes, side effects can occur if the medicine is absorbed into your bloodstream. Call your doctor right away if you have:

Also call your doctor if you have:

Common Istalol side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Istalol?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Tell your doctor about all your current medicines and any you start or stop using, especially:

This list is not complete. Other drugs may interact with timolol ophthalmic, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Istalol only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.