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Tigan suppositories

Generic name: trimethobenzamide/benzocaine [ trye-METH-oh-BENZ-a-mide/BEN-zoe-kane ]
Brand name: Examples include Tebamide and Tigan

Use with caution in children. Tigan suppositories are not recommended for normal vomiting and should be limited to vomiting of known origin. Caution is advised because of the following: similar medication may contribute, along with viral illnesses, to development of Reye syndrome; symptoms that may appear may be confused with a primary disease responsible for vomiting; this medication may change the course of Reye syndrome. Do not use in children who show signs/symptoms of Reye syndrome (severe and continued vomiting, drowsiness, lethargy, behavior changes, and seizures) unless other methods of controlling vomiting are not successful.


Tigan suppositories are used for:

Treating nausea and vomiting. It may also be used for other conditions as determined by your doctor.

Tigan suppositories are an antiemetic. It works by blocking one of the chemical messengers that stimulates nausea and vomiting.

Do NOT use Tigan suppositories if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tigan suppositories:

Some medical conditions may interact with Tigan suppositories. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Tigan suppositories. Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tigan suppositories may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tigan suppositories:

Use Tigan suppositories as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Tigan suppositories.

Important safety information:

Possible side effects of Tigan suppositories:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; rectal irritation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); loss of balance; seizures; shuffling walk; uncontrolled movements of the arms or legs; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Tigan suppositories:

Store Tigan suppositories in the sealed wrapper at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tigan suppositories out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Tigan suppositories. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: June 3, 2015

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.